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Probably primarily due to the higher amount of myelin content/debris, a significantly stronger microgliosis can be observed in the cerebellar white matter as compared to the gray matter structures (Skripuletz et al., 2008

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As positive control, we exposed cells to the GSH-synthesis inhibitor L-buthionine-sulfoximine (L-BSO), which was shown to induce oxidative stress but not cytotoxicity in HCT116 cells 24, 25