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It is the only peptide in this guide that is FDA-approved with a primary indication for reducing abdominal fat, placing it in a unique regulatory position among the best peptides for weight loss targeting visceral adiposity

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It is crucial to compare the NAD vs B12 injections or shots

For patients seeking weight loss who request B12 injections, GPs should: Assess for genuine deficiency through appropriate blood tests rather than empirical treatment Provide education about the lack of evidence supporting B12 for weight loss in non-deficient individuals Explore underlying concerns about weight and energy levels, addressing these through appropriate channels Signpost to evidence-based resources such as NHS weight management services according to local pathways Patients should contact their GP if they experience unexplained fatigue, neurological symptoms (numbness, tingling, balance problems), or signs of anaemia (pallor, breathlessness, palpitations), as these may indicate B12 deficiency requiring investigation

Guidotti G, Brambilla L, Rossi D