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doi: 10.3389/fnut.2025.1678150 Received 04 August 2025 Accepted 02 October 2025 Published 06 November 2025 Volume 12 - 2025 Edited by Hengyi Xu, Nanchang University, China Reviewed by Jashbhai B

The physiologic requirements for GSH by key cell types of the immune system, and the ability of macrophages to take up intercellular GSH, as well as to metabolically interact with T-lymphocytes to indirectly cause their GSH to increase, offer additional reasons to attempt to correct the GSH deficiency in HIV/AIDS