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As shown in Figure 1 from our 2013 paper, the ECS consists of the classical cannabinoid receptors 1 and 2 (CB1 and CB2) along with the endocannabinoids that activate them, primarily anandamide and 2-arachidonylglycerol (2-AG), and the enzymes responsible for their synthesis and degradation

Sivaraj, D

This points to the possibility that the peptide could influence extracellular matrix maintenance, hydration, and skin barrier strength in laboratory settings

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