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1, 2, 6, and S4 were generated in part with Biorender.com

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7 A recent randomized, double-blind, placebo-controlled clinical trial to assess the efficacy of 3% propolis ointment (Herstat) in patients with a history of HSV-1 infection showed a mean healing time of 6.24 days, compared to 9.77 days in the placebo group, along with better pain relief

In contrast, Phenylbutazone showed radioprotective effects in H2AX but failed to restore saliva secretion, possibly due to the long-term toxicity effects of corn oil used as a solvent (Fig

Gentle exercise is best in this case