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doi: 10.3390/ijms19061804 57

doi: 10.1016/j.jaci.2011.03.031 13 GaoX.LeeK.ReidM

J Biol Chem 1993

Cell 185 , 831846.e14 (2022)

However, even though the levels of L-lysine and ATP are high enough, -PL cannot be accumulated efficiently if there is insufficient Pls activity

Notably, the key components of the IL-6/JAK signaling pathway, including Jak2 and Il6ra, were significantly downregulated, which aligned with the observed suppression of JAK2/STAT3 signaling at the protein level