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doi:10.1016/j.autrev.2009.02.020 Bravenboer B, Kappelle AC, Hamers FP, van Buren T, Erkelens DW, Gispen WH

This increase in arginine levels in the mutant exposed to iron directly correlates with the decrease in the abundance of the repressor ArgR, which could be regulating the arcA genes (EF0104, encoding arginine deiminase), arcF (EF0105, encoding ornithine carbamoyltransferase) and argC (encoding carbamate kinase), all of which are derepressed in the mutant compared to the WT

reported that activation of the NLRP3 inflammasome, including increased mitochondrial superoxide production and lipid peroxidation, may persist after short-term patient recovery [80]