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Pena-Leon V, Folgueira C, Barja-Fernndez S, Prez-Lois R, Da Silva Lima N, Martin M, et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 298.Jrah-Harzallah H., Ben-Hadj-Khalifa S., Almawi W.Y., Maaloul A., Houas Z., Mahjoub T

Some of the first symptoms of a metabolic crisis are: extreme sleepiness behavior changes irritable mood poor appetite Other symptoms then follow: fever nausea diarrhea vomiting hypoglycemia If a metabolic crisis is not treated, a child with CTD can develop: breathing problems swelling of the brain seizuresThese are also called "convulsions" or "fits." During a seizure, a person loses consciousness and control of his or her muscles

For RNA sequencing, day 5 adult worms were selected, as they exhibited a more pronounced phenotype in the mobility assay observed at later stages

A precise human half-life figure from a published human PK study is not something this review can cite with confidence