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In this context, developing a strategy to target renal fibrosis is essential for effective treatment of patients with kidney disease

Moreover, curcumin exerts antioxidant, anti-inflammatory, and antifibrotic properties and reduces kidney cyst size and number in mice [45,54]

Therefore, AS-IV can inhibit inflammatory infiltration and fibrosis-induced myocardial damage

In laboratory studies, TB-500 has been evaluated for its interaction with actin-binding pathways, cytoskeletal organization, and cellular migration processes