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Tesaglitazar feeding did not alter plasma triglycerides or glucose levels (Figure 1, A and B) and neither did it affect weight gain rate and food consumption compared with respective controls (Supplemental Figure 1, A and B

Citation [1] Park JR, Lee H, Kim SI, Yang SR

Upon completion of the treatment, plasma triglycerides (TG

Reduces oxidative damage to cells and DNA, which is a primary driver of visible aging and tissue degradation

As treatment with tesaglitazar reduced mitochondrial abundance and respiratory capacity, we tested whether it also affects cardiac lipid content

4 Future research directions and prospects The role of SIRT1 in the regulation of ferroptosis has emerged as a promising area of research with significant therapeutic potential in a multiple of diseases