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Following the induction of oxidative stress, ROS levels are increased and these abundant ROS activate mitophagy, which is a remedial measure to prevent cell death [116]

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Notably, entosis represents an interesting example of oncogenedriven cellcell competition, as KRastransformed cells were found to be more likely to consume their nontransformed neighbors than be engulfed themselves (Sun et al , 2014)

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Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinsons disease