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Many chronic diseases, such as cancer and cardiovascular and neurological diseases, have a multifactorial origin

Disruption of these antioxidant systems may promote oxidative stress that could induce damage to the biomolecules and cause various cancers

Ozone is a strong oxidizing agent and is slightly less reactive than hydroxyl radicals (Travagli and Iorio 2023)

The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders

30 , 31 , 32 , 33 The direct interaction between GSTP1 and STAT3 can promote HCC progression, 8 and our previous study found that GSTP1 could be ubiquitinated by FBX8, thus inhibiting its function in promoting CRC proliferation, invasion and metastasis

Although the mechanism(s) underlying NASH progression remain to be fully elucidated, accumulating evidence suggests that both oxidative stress and the pro-inflammatory cytokine tumor necrosis factor- (TNF) are critical contributors in this process 5