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Supplements Vitamin B 12 is available over-the-counter as a single-nutrient supplement and also as a component of multivitamin and vitamin B-complex supplements (129)

B12 Deficiency: Widespread, yet too Often Undetected How common is B12 deficiency

Research suggests it may act through beta-3 adrenergic pathways or through non-receptor-mediated effects on adipocyte lipid metabolism, rather than through classical GH receptor signaling

[DOI] [PMC free article] [PubMed] [Google Scholar] 338.Grudzien-Nogalska, E., Bird, J

Additionally, a very small percentage of B12 from a supplemental dose is absorbed by passive diffusion

Therefore, you need to get it from your diet (food sources) or dietary supplements in order to make enough red blood cells and other important functions