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CrossRef Tenofovir alafenamide alleviates nonalcoholic steatohepatitis in mice by blocking the phosphorylation of AKT in intrahepatic mononuclear phagocytes Pu Reun Roh, Sung Min Kim, Byung-Yoon Kang, Kyoung Do Mun, Jong Geun Park, Min Woo Kang, Wonhee Hur, Ji Won Han, Heechul Nam, Seung Kew Yoon, Pil Soo Sung Biomedicine & Pharmacotherapy .2022

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The preparation of freeze-dried powder is divided into two types in the existing freeze-drying process, wherein the first type is to freeze-dry raw materials, crush and screen the raw materials under the aseptic operation condition and fill the powder, although the freeze-drying cost is low, the reduced glutathione powder for injection prepared by the method is easy to absorb moisture, decompose and deteriorate, the medication safety is influenced, and the insufficient filling amount is easy to cause

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For example, -KG acts as a cofactor for the activation of the histone demethylase JMJ family (Jumonji) to promote histone demethylation (102, 125)