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10.1111/j.1432-1033.1990.tb15401.x [DOI] [PubMed] [Google Scholar] Dock-Bregeon AC, Garcia A, Gieg R, Moras D

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Although anti-cancer therapy targeting metabolism has achieved some gratifying results, it is still currently believed that this field has the following shortcomings for possible future breakthroughs: 1) The side effects of such drugs limit their clinical effects as the optimal dose window is hard to be determined