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Similarly, Doll and colleagues showed that the rapid MOR dephosphorylation at S375 involves the protein phosphatase 1 which increases the recycling of receptors contained in endosomes to cell surface (Doll et al., As indicated above, DOR was initially described as a receptor sorted to lysosomal degradation (Tsao and Von Zastrow, 2000)

Consistent with these findings, we noted stromal contact-mediated induction of GCLC and xCt expression (Supplementary Fig

[22] showed that glutamine supplementation promotes anabolic signaling by modulating AMPK and mTOR signaling pathways involved in skeletal muscle protein metabolism, particularly when combined with exercise

However, UBQLN2 knockout did not affect the formation of G3BP1- and eIF4G1-positive SG puncta after 3 h of AsNaO treatment in our cell system (Fig

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Microautophagy is a process where the lysosome directly engulfs small portions of the cytosol by membrane invagination or protrusion to internalize cytosolic cargo into intraluminal vesicles within the lysosome