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While our study has shed light on a prospective protective function for astaxanthin against GUD, further mechanistic studies are needed to rule out the major downstream key players involved in this effect

10.1016/j.visres.2006.12.015 Vis

In line with this, a study in rotating shift workers from the automotive industry found that NSW significantly reduced plasma concentrations of multiple immune markers, including pro- and anti-inflammatory cytokines (TNF-, IL-2R, IL-1RA, IL-4, IL-12, IL-17), chemokines (IP-10, MIP-1, MIP-1, RANTES), and growth factors (EGF, FGF, VEGF), indicating a broad suppression of immune pathways linked to circadian disruption and higher susceptibility to infection and cancer 113

Fat-soluble vitamins are handled like lipids and thus are incorporated into chylomicrons that have triglycerides removed by lipoprotein lipase

Notably, these pharmacological features are conceptually consistent with the traditional Chinese medicine theory of deficiencystasisturbidity, which shows notable parallels with contemporary understandings of mitochondrial dysfunction, disordered lactate metabolism, and aberrant histone modifications in diabetic nephropathy [62, 63]

The relationship between Cytomegalovirus infection and Guillain-Barre syndrome