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and indirectly, as the essential co-substrate for glutathione peroxidase (GPx) and glutathione S-transferase (GST) enzymes that detoxify hydrogen peroxide, lipid peroxides, and electrophilic compounds

M.HammettA

Other than this, we observed no alterations in serum glucose, total protein, albumin, globulin, or albumin: globulin ratio across groups, suggesting that Se level in CON_HS was adequate for maintaining these attributes during HS, as also reported by Kumar et al

Ferranti R, da Silva MM, Kowaltowski AJ

demonstrated that Tom20 or Bax knockout effectively blocks ROS-induced pyroptosis, while antioxidant treatment significantly reduces Tom20 oxidation, Bax mitochondrial recruitment, and GSDME cleavage, further confirming that ROS serves as the central regulator of this signaling pathway (47)