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Lingvay I, Sumithran P, le Roux CW, Cohen RV

The research in human clinical settings is limited

Age, sex, BMI, diabetes status, genetic markers, microbiome composition, and lifestyle factors all influence outcomes

2013;8:e54113

Vitamin B12 deficiency affects up to 20% of older adults, and GLP-1 medications like semaglutide can further reduce B12 absorption by slowing gastric transit