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10.1124/jpet.105.094599 J

Protein quality control is central to maintaining cellular homeostasis

Cultures were subsequently cooled in an ice water bath for 15 min and centrifuged (4.000 g , 15 min, 4 C)

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Zito E, Melo EP, Yang Y, Wahlander , Neubert TA, Ron D (2010) Oxidative protein folding by an endoplasmic reticulum-localized peroxiredoxin

Although the effects of sGC modulators on noncanonical ERK1/2-mediated signaling were outside the scope of this study, a cGMP analog (8Br-cGMP) was able to partially rescue ERK1/2 phosphorylation, necessary for the suppression of the initial response to TGF-1