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Islets showing strong staining in a minority of cells coupled with moderate staining in most islet cells were assigned grade 6

(2004) Regulation of gene expression by a metabolic enzyme

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Furthermore, it has been found that modulation of the Nrf2 signalling pathway by triterpenoids compounds results in a significant increase in survival in the SOD1 G93A mouse model of ALS, thereby indicating that activation of Nrf2 has a neuroprotective effect [268]