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Human research on sermorelin itself is limited, but a few clinical studies of GHRH analogues in humans provide the best available evidence that stimulating the somatotropic axis can support growth hormone secretion with downstream effects on body composition and recovery

For some it can cause the heart to race or the body to become overstimulated, agitated or even anxious in some cases

doi: 10.1038/bdjteam.2016.62 12 ChenQ.ShiJ.YuG.XieH.YuS.XuJ.et al

While the science on whether this local application significantly outperforms systemic is still developing, the anecdotal reports from the research community are what keep this method at the forefront of the conversation

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[DOI] [PubMed] [Google Scholar] 31.Barcelo A, Claustre J, Moro F, Chayvialle Ja, Cuber JC, Plaisanci P