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[0339] The compound of Formula la at 100 mg/mL in water with 0.1% w/v HPMC, 0.5% w/v poloxamer 237, and 0.9% sodium chloride: The suspension vehicle containing the excipients HPMC, poloxamer 237, and sodium chloride was prepared as described above in Example 3

2.4.3 Chitosan Chitosan is a natural polysaccharide derived from the deacetylation of chitin, commonly found in the shells of crustaceans such as shrimp and crab

Notably, the optimal in vivo neuroprotective dose was identified as 0.5 mg/kg, which produced substantial behavioral and histological improvements

[CrossRef] [Google Scholar] Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

Furthermore, for specific compounds, additional key mechanisms such as Fas-mediated signal transduction, loss of cellular redox homeostasis, ATP depletion, changes in ion channels, and activation of kinases and caspases, among others, have been highlighted

AOD 9604 lyophilized powder should be stored frozen at -20 degrees C until ready for reconstitution