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If needed, increase to 1 mg for additional blood glucose control

A review of pharmacology, toxicity and pharmacokinetics of 2,3,5,4-tetrahydroxystilbene-2-O-beta-D-glucoside

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In accordance to the activation of HIF-1 (Figure 5A), roxadustat significantly increased the PFKFB3 expression on mRNA and protein level in a dose-dependent manner in both neurons and astrocytes (Figure 8B)