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Site rotation across these regions on a weekly basis is standard practice for all once-weekly subcutaneous peptide administrations, and is particularly important during extended retatrutide dosing studies where repeated injection at a single site can cause localized lipodystrophy or reduced absorption efficiency

Research has examined its effects on body weight reduction, appetite regulation, metabolic outcomes, and combination therapy with semaglutide for obesity management and metabolic disease research

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Always inform your healthcare provider about all medications and supplements you are taking