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Although those compounds induced both cell death and modulated the autophagy process, the autophagy perturbation itself may not have been the causative incident

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However, there are disputes about the relevant applicability of this evidence [18, 19], particularly considering the low survival rate of bone marrow stromal cells transplanted into the contused adult rat spinal cord [20, 21] and the need to completely fill the lesion site with neural stem cells [22]

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