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Hepatocyte growth factor (HGF) is showing a strong anti-fibrotic effect with remarkable effectiveness in ameliorating tissue fibrosis in a wide range of animal models HGF exhibits a remarkably powerful anti-fibrotic effect that ameliorates tissue fibrosis in a wide range of animal models and tissues (Liu and Yang, 2006)

Side effects such as drowsiness, dizziness, nausea and vomiting, dry mouth, drug high, and others were reported in studies included in the systematic review, though none were severe