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Description

The STITCH database includes many potentially important off-targets to particular compounds (derived from experimental data, other curated databases or text mining) in addition to the primary known targets, and all protein-compound interactions in STITCH have an associated confidence metric

Nutraceuticals from bitter leaf ( Vernonia amygdalina Del.) protects against cadmium chloride induced hypertension in albino rats

Neurotoxicology 91:100118

extract and gallic acid attenuate lps-induced inflammation and oxidative stress via MAPK/NF-B and Akt/AMPK/Nrf2 pathways

This process culminates in lactate production via LDHB (EC50 = 80 M), as confirmed by pharmacological inhibition of glutamate transporters (THA/L-CCG III) and Na + substitution experiments