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This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol

This restoration of metabolic cofactor availability enables enhanced function of NAD+-dependent enzymes including sirtuins, poly(ADP-ribose) polymerases, and various deacetylases that regulate cellular metabolism, stress responses, and aging processes

Activin B inhibits lipolysis in 3T3-L1 adipocytes

Finally, this intermediate called cystathionine ends up being converted into cysteine

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