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Description

Source data related to metabolomic analyses are included in Supplementary Data 1 (comparisons of primary tumours and PDX) and Supplementary Data 2 (comparison of HBCx-124 and HBCx-137 control and IACS-treated xenografts)

Csorba, N., brnyi-Balogh, P

L.PlewaC.EllisonA

222:jeb200246

Acknowledgements This study was financially supported by the China Agriculture Research System of MOF and MARA (No

It has been reported that tumor-surrounding adipocytes exhibit an distinct phenotype comparing to normal adipocytes, which is characterized by upregulated beige/brown adipose markers and increased catabolism and the release of metabolites, including lactate, free fatty acids, pyruvate, and ketone bodies