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Chronic inflammation leads to increased ROS production, which can result in somatic mutations

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In addition, a parallel study also reported altered lipid profiles, lipoprotein composition, and oxidant and antioxidant levels in child CD patients.[] Also, DOdorico et al .[] were the first to demonstrate the importance of antioxidant depletion through increased free radical peripheral leukocyte DNA damage and decreased plasma antioxidant defenses found in malnourished IBD patients

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As we age, our NAD+ levels naturally decline, leading to fatigue, cognitive decline, and a weakened immune system

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