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The safety of the plastic has been confirmed by tests in according to USP biological standards for plastic containers
Kang L, Jiang D, Ehlerding E, Barnhart T, Ferreira C, Wang R, et al
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Serious bacterial infections requiring hospitalization or intravenous antibiotics may occur and appear to be more prevalent during the first 6 to 12 months of TNF inhibitor therapy, likely because patients at greatest risk may develop this complication early, then discontinue therapy
