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ROS generation was detected using a Leica fluorescence microscope (Leica DM6000B) and Leica LAS X software, and the quantitative analysis was performed with ImageJ

In addition to the inhibition of arachidonic acid metabolism by COX inhibition, other possible mechanisms for the multiple effects of ASA include increased ROS production, alterations in mitochondrial function, cell signaling and induction of apoptosis [7], [19], [30], [31], [32], [33]

Research interest in this peptide centers on its selectivity: it does not appear to elevate IGF-1 levels in studied models, distinguishing it mechanistically from full growth hormone

159 Pursuing this finding in relation to neonatal hyperbilirubinemia, Lin et al

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Insulin-like growth factor 1 impact on Alzheimers disease: role in inflammation, stress, and cognition