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Thiry C, Ruttens A, De Temmerman L, Schneider Y-J, Pussemier L

SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside

Expert Opinion on Biological Therapy, 12 (1), 3751

Science 262, 896900

After internalization of the microorganism has occurred, NADPH oxidase, located in the leukocyte cell membrane, is activated and reduces O 2 from the surrounding tissue to superoxide (O 2 - ), a free radical, as NADPH is oxidized