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Mittelbronn et al., 2001

As the only known acetyltransferase in eukaryotes, its structure includes an acetyltransferase domain, a tRNA-binding domain, and an RNA helicase domain [314]

Supplementation with vitamin E has been shown to attenuate BBB leakage and protect against cognitive impairment following I/R injury, suggesting its potential as a protective agent for the BBB (Freeman and Keller, 2012