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Exposure of human lung epithelial (A549) cells to acrolein (150 fmol/cell for 1 h) first depleted 80% of the intracellular GSH pool and then increased the transcription of -glutamylcysteine synthetase at 6-12 h post-treatment, resulting in normalization of GSH levels

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for ifn-gamma

Wang et al., 2004

2-Hydroxylated and 4-hydroxylated estrogen exerts biologic responses on the cyclic secretion of leutenising hormone (LH) perhaps even on follicle stimulating hormone (FSH) and prolactin

Additionally, by validation in an independent second patient cohort (n=156), we successfully replicated the high-performance predictions for F0/F1 and F3/F4 fibrosis stages with an AUC of 0.84