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Description

These differences were addressed by assessing the consistency of results across various types of studies (e.g., in vitro and in vivo ) and study designs

10.1016/j.jep.2023.117438 24 BayrH.AnthonymuthuT

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Common symptoms include right upper quadrant pain and fatigue

About 55% of the variability in warfarin dose could be explained by the combination of VKORC1 and CYP2C9 genotypes, age, height, body weight, interacting drugs, and indication for warfarin therapy in Caucasian patients.5Similar observations have been reported in Asian patients.6,7 The terminal half-life of warfarin after a single dose is approximately one week