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Linear mixed effects (LME) models Linear Mixed Effects (LME) models are extensions of simple linear models, which account for both fixed effects and random effects, that adjust for dependencies due to multiple time-linked assessments coming from the same participant

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How Dihexa Works (Proposed and Partly Retracted) The proposed mechanism is that Dihexa potentiates hepatocyte growth factor (HGF) signaling at the c-Met (MET) receptor, downstream of PI3K-AKT, driving dendritic spine formation and synaptogenesis