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Glutathione homeostasis and functions: potential targets for medical interventions

PPa-S-PTX remains stable in its inactive state and releases PTX and PPa only in the presence of excessive ROS within tumor cells

Fuster et al., 1998), glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and glutathione reductase (Kucharczyk et al., 2023) and X (Malebari et al., 2020), respectively, whereas loop diuretics can interfere with signaling mediated by GABA A receptors (Korpi and Luddens, 1997