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Animal studies have shown good tolerability across multiple administration routes including oral, intraperitoneal, intramuscular, and topical applications

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For instance, it healed transected muscles and counteracted NSAID toxicity without adverse effects.[24][25] Clinical Trials : A Phase I trial (NCT02637284) confirmed safety and pharmacokinetics in healthy volunteers, with no serious adverse events.[26] Phase II trials for ulcerative colitis showed encouraging results, with BPC-157 promoting remission.[27] A recent trial in inflammatory bowel disease patients reported tolerability and potential benefits.[28] The table below highlights select key studies: While robust, the reliance on animal models underscores the need for more large-scale human trials

BPC-157 is a peptide composed of 15 amino acids, in a sequence of: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val BPC-157 has enhanced stability compared to other peptides, and is one of the only peptides that is available to be taken as an oral supplement

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But Brunner argues that designing for the problem is the better path