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The intricate and complex interplay between glucose homeostasis, hypoxia and neovascularization warrants further investigation

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An illustrative example is the approval of cabozantinib (Cabometyx R), which acts as a VEGFR inhibitor, along with inhibiting cMET and AXL

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Melanotan 1 is a linear 13-amino-acid analog of -MSH (afamelanotide) that mainly activates the MC1R pigmentation receptor

The performance of each model was evaluated using cross-validation on the training set, with metrics including the area under the receiver operating characteristic curve (ROC-AUC), accuracy, sensitivity, and specificity