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Methodological issues in combining diverse study types in systematic reviews

doi: 10.1016/j.psj.2022.102189 109 Al-KhalaifahHSIbrahimDKamelAEAl-NasserAAbdelwarithAARoushdyEMet al

The early view that these channels are present only in non-excitable cells is not true

MR is based on the random allocation of alleles from parents to offspring, ensuring that the formation of fertilized eggs and fixed genotypes remain unaffected by the disease

Limitations of conventional therapies Modern pharmacological strategies for GI disorders rely on drugs such as antacids, proton pump inhibitors (PPIs), H 2 receptor antagonists, anti-inflammatory agents, antibiotics, and laxatives

This review aimed to explore the molecular mechanisms underlying APAP-induced liver injury, particularly inflammasome activation, and evaluate the current and emerging therapeutic strategies