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Affiliation: 1 DevelRx Ltd, Biocity, NG1 1GF Nottingham, UK Email: [email protected] ORCID: Affiliation: 1 DevelRx Ltd, Biocity, NG1 1GF Nottingham, UK 3 Department of Life Sciences, University of Bath, BA2 7AY Bath, UK Explor Neuroprot Ther

they subsequently employed a molecular dynamics-driven computational strategy to guide SELEX optimization, yielding a superior DNA-based aptamer ( dp53m ) (Fig