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doi: 10.1104/pp.109.3.1047 24 GiannopolitisC

-Glutamylcysteine ligase expression is subject to regulation by Nrf2, a transcription factor that regulates a wide array of antioxidant responsive element (ARE)-driven genes in various cell types, and thus plays a central role in cellular antioxidant defenses (Jaiswal, 2004

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found that silencing human cysteine dioxygenase 1 (CDO1) led to the inhibition of Erastin-induced ferroptosis in GC cells

This finding suggests that asymptomatic individuals may harbour low-level infections that are not detected by standard diagnostic test, highlighting a potential gap in malaria detection and the importance of further research in surveillance of asymptomatic malaria