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P62/IMP2, an oncofetal protein, was initially reported as a tumor-associated antigen in HCC

But Rosanna Squittis research group in Italy has spent over a decade showing that ATP7B variants, not the severe mutations that cause Wilsons but milder polymorphisms, turn up more often in Alzheimers patients than in matched controls

Neurotox Res 41(6):670680

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Product specifications Strength 10mg SKU bpc-157_10mg Batch VTL-3664990 Use Research use only Certificate of analysis This batch's lab report Independently tested

From these findings and the fact that glutathione is essential for lymphocyte proliferation and immune responses, , we hypothesized that abundant cystine/cysteine in the kidneys forms a unique metabolic microenvironment that supports ectopic lymphocyte proliferation, leading to the formation of TLS