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However, when viral infection, environmental stress, or immunosuppression impairs these defenses, microbes from the oral cavity and URT can aberrantly colonize the LRT, markedly increasing the risk of BRD through pathogenic mechanisms and microbial agents similar to those described in the URT section above

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The Se and F + Se groups also did not show differences between them but with group C

doi: 10.1016/j.gie.2007.03.006 66 LeeJKAgrawalDThosaniNAl-HaddadMBuxbaumJLCalderwoodAHet al

Kayode , Sina Kazemian , Shemsu Kedir , Tibebeselassie S