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Alcohol consumption and metabolic syndrome: Clinical and epidemiological impact on liver disease

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Resveratrol, in particular, has been shown to inhibit CYP1b1 (decreases 4-OH production and improves the 2OH/4OH ratio), inhibit CYP3a4 (decreases 16-OH-E1 production and improves the 2OH/16OH ratio), induce oxidative pathways such as Nrf2, and induce quinone reductase which may help reduce estrogen semi-quinones back into catechol estrogens

Mice were divided into 4 groups containing 8 animals each: sedentary control, sedentary supplemented with glutathione, exercise control, and exercise supplemented with glutathione