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found that in the mouse mode heme oxygenase 1 (HMOX-1), heat induced and regulated by early growth response factor 1 (EGR1), can mediate ferroptosis in KCs and cause liver injury [47]

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Combined Iron Chelator with N-Acetylcysteine Exerts the Greatest Effect on Improving Cardiac Calcium Homeostasis in Iron-Overloaded Thalassemic Mice

OexnerRRAhnHTheofilatosKShahRASchmittRChowienczykPet alSerum metabolomics improves risk stratification for incident heart failure

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Patten CJ, Thomas PE, Guy RL, Lee M, Gonzalex FJ, Guengerich FP, Yang CS: Cytochome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics