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In this study, we demonstrated the potential of modulating the host microenvironment to sensitize intracellular persisters to antibiotics and improve treatment outcomes

Leuk Res 25:112 Liu Q, Kriksunov IA, Graeff R, Munshi C, Lee HC, Hao Q (2005) Crystal structure of human CD38 extracellular domain

It may be due to impaired transport of folate into the brain or increased folate metabolism within the brain

Data Animal Data In pregnant rats given twice weekly subcutaneous doses of 0.02, 0.1, and 0.5 mg/kg tirzepatide [0.03-, 0.07-, and 0.5-fold the maximum recommended human dose (MRHD) of 15 mg once weekly based on AUC] during organogenesis, increased incidences of external, visceral, and skeletal malformations, increased incidences of visceral and skeletal developmental variations, and decreased fetal weights coincided with pharmacologically-mediated reductions in maternal body weights and food consumption at 0.5 mg/kg