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Here two different pharmacological agents known to induce gut permeability (ethanol and AT1002, a Vibrio cholerae zonula occludens toxin hexapeptide) were used to induce transient increase in gut permeability in mice before their exposure to experimental colitis

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Furthermore, cuprizone intoxication is a useful tool for studying the processes of remyelination, as withdrawal of cuprizone typically results in remyelination in the CNS of the intoxicated animal 21 , albeit at a significantly slower rate following chronic cuprizone intoxication 22

BPC-157's gastric origin gives it natural relevance to gut research, and published work has characterised its activity in models of gastric ulceration, intestinal anastomosis, and inflammatory bowel injury

BPC-157 has been investigated for its potential to restore calcium balance and alleviate associated health issues

Srivastava et al., 2021)